Discover How Healthy Flow Blood Supports Daily Vitality

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What's glycogen storage illness? Glycogen storage diseases (GSDs) are a bunch of rare situations during which your body can_t use or store glycogen correctly. They_re varieties of inherited (handed from mum or dad to youngster) metabolic disorders. Advertising on our site helps help our mission. We do not endorse non-Cleveland Clinic services or products. Glycogen is the stored type of glucose (sugar). Glucose is your body_s fundamental supply of vitality. It comes from carbohydrates (a macronutrient) in certain foods and fluids you eat. When your physique doesn_t instantly want glucose for vitality, it shops glucose primarily in your skeletal muscles and liver as glycogen for later use. Your body creates glycogen from glucose through a course of referred to as glycogenesis. When your body wants extra gas, it breaks down glycogen to be used by way of a process known as glycogenolysis. Several enzymes are chargeable for these two processes. Glycogen storage diseases occur while you don_t have one or more of these enzymes. Your physique can_t use saved glycogen for vitality or maintain regular Healthy Flow Blood solution glucose levels. This could cause a number of points, together with frequent symptomatic low blood sugar (hypoglycemia), liver harm and muscle weakness. Researchers know extra about some types than others. GSD mostly impacts your liver or muscles. Some varieties trigger issues in different areas of your physique, as effectively. For each sort of GSD, there_s a lack (deficiency) of a sure enzyme involved in glycogen storage or breakdown. Healthcare providers may refer to each kind based mostly on the specific enzyme that_s lacking or the scientist who discovered that type of GSD. Glycogen storage illness is uncommon. GSD kind I (von Gierke illness), the commonest sort, happens in roughly 1 in 100,000 births.